EnteriX:

Visualization Tools for Bacterial Genome Alignments



Salmonella view The Computational Biology Group
Department of Computer Science
George Washington University

This site allows comparative views of a reference genome (either E. coli K-12 or O157:H7, S. typhimurium LT2, S. typhi CT18, S. paratyphi A or K. pneumoniae) with sequences from several related bacteria using three different visualization tools. The Enteric server offers large-scale views of pairwise alignments, with point-and-click capabilities to retrieve related gene and alignment information. The Menteric tool displays nucleotide-level multiple alignments of the bacterial sequences, along with regulatory site annotations which the user interested in conservation and functional studies may want to explore further.

Each tool is accompanied by documentation on its features and provides links to related sites of potential interest, for easy navigation.
 

        Enteric PIPs     The Enteric server

        Menteric multiple alignment     The Menteric server


Enterix has moved from its previous home at Penn State.

If you use this software in a publication, please cite:

A complete list of relevant bibliographical references is here.



Bacterial sequences used in comparative views


With several E. coli and Salmonella genomes completely sequenced and partially characterized, and sequence data (whole genome and contigs) from several related genera of enteric bacteria becoming available, the set of enteric eubacteria is particularly well suited for comparative studies.

The sequence and annotation data presented here were obtained from the following sites:

Species Abbr. Project & Source Stage
Escherichia coli K12 ECO U. of Wisconsin; NCBI
Complete
E. coli enterohemorrhagic strain O157:H7 EDL933 ECH U. of Wisconsin; NCBI
Complete
Escherichia coli CFT073 ECU U. Wisconsin; NCBI
Complete
Escherichia coli 042 ECA Sanger Center Complete
Escherichia coli E2348 ECP Sanger Center Contigs
Shigella flexneri 2a str. 301 SHG Microbial Genome Center ChMPH; NCBI Complete
Shigella dysenteriae M131649 SHD Sanger Center Contigs
Shigella sonnei 53G SHS Sanger Center Complete
Salmonella typhimurium LT2 STM WUSTL; NCBI
Complete
Salmonella typhimurium 14028 STA, STF SKCC Contigs
Salmonella typhimurium SL1344 SSL Sanger Center Contigs
Salmonella typhi CT18 STY Sanger Center; NCBI
Complete
Salmonella typhi Ty2 STT U. Wisconsin; NCBI
Complete
Salmonella paratyphi A SPA WUSTL; NCBI
Complete
Salmonella paratyphi B SPB WUSTL; NCBI
Contigs
Salmonella paratyphi B SARB47 SPB WUSTL
Contigs
Salmonella enteriditis PT4 SEP Sanger Center Complete
Salmonella enteriditis SEN U. of Illinois, Urbana Champaign Contigs
Salmonella enteriditis SARB17 SPR WUSTL
Contigs
Salmonella dublin SDU U. of Illinois, Urbana Champaign Contigs
Salmonella gallinarum SGA Sanger Center Complete
Salmonella Newport SL317 SNE TIGR/JCVI Complete
Salmonella Newport SL254 SNL TIGR/JCVI Complete
Salmonella salamae (ssp. II) SSA WUSTL
Contigs
Salmonella diarizonae (ssp. IIIb) SDI WUSTL Contigs
Salmonella arizonae (ssp. IIIa) SAR WUSTL Contigs
Salmonella houtenae (ssp. IV) SHO WUSTL Contigs
Salmonella bongori SBO Sanger Center Complete
Klebsiella pneumoniae KPN WUSTL Complete
Klebsiella oxytoca KOX WUSTL Contigs
Erwinia carotovora subspecies atroseptica SCRI1043 ERC Sanger Center; NCBI
Complete
Erwinia amylovora ERA Sanger Center Complete
Serratia marscenses SMA Sanger Center Complete
Yersinia pestis CO92 YPE Sanger Center; NCBI
Complete
Yersinia enterocolitica (type 0:8) YEN Sanger Center Complete
Vibrio cholerae VCH TIGR; NCBI
Complete
Pseudomonas aeruginosa strain PAO1 PAE Pseudomonas Genome Project Complete
Enterobacter sakazakii ESA WUSTL; NCBI
Complete
Citrobacter koseri CKO WUSTL; NCBI
Complete
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This service is provided by the GWU Computational Biology group (Liliana Florea), in collaboration with the Penn State Center for Comparative Genomics and Bioinformatics (Webb Miller, Cathy Riemer, Scott Schwartz), Sidney Kimmel Cancer Center (Michael McClelland), and the Genome Sequencing Center at Washington University, St. Louis (Richard Wilson).